The science behind deadly corona virus



Corona viruses are considered a large family of viruses that cause illness ranging from the common cold to more severe diseases.

The name comes from the Latin word "corona", which means "crown" or "halo", and refers to the shape of the virus particle when viewed under a microscope.

"Corona viruses are transmitted between animals and people," the WHO says.

Common signs of infection include respiratory fever, symptoms, cough, breathing and shortness of breath difficulties. In more severe cases, the infection can cause pneumonia, severe acute respiratory syndrome (SARS), kidney failure and even death,

But what is this COVID-19 being referred to everywhere?

It's the disease caused by SARS-COV-2 the virus behind COVID-19 originated in Wuhan, China.

An important fact that you people should know about coronavirus and COVID-19, coronavirus is the natural virus that originates from the core of mother Earth but COVID-19 is a human processed virus.

Luc Montagnier is a France virologist who got Nobel prize(2008) for his discovery of human immunodeficiency virus, he claimed after all of his experiments that the 'novel coronavirus' is processed in somewhere at chine lab.

'China is known to be the parent of viruses'

The truth about corona virus and COVID-19

 SARS corona virus (SARS-CoV) – virus identified in 2003. SARS-CoV is thought to be an animal virus from an as-yet-uncertain animal reservoir, perhaps bats, that spread to other animals (civet cats) and first infected humans in the Guangdong province of southern China in 2002, but SARS-COV-2 is the virus behind COVID-19 pandemic, although they are genetically related but different in action. The coronaviral genome encodes four major structural proteins: the spike (S) protein, membrane (M) protein, nucleocapsid (N) protein, and the envelope (E) protein. The envelope protein of SARS-COV gets intentionally altered to get SARS-COV-2 and make it worse for humans as it specifically goes for the human ACE-2 receptor. The study published in science that the virus targeted the type of receptors found in human lung, kidneys, and intestine. The virus seems to attack two types of lung cells- goblet cells that coat the respiratory tract with mucus and ciliated cells that usually filter out pathogens. The virus ‘SARS-CoV-2’s key, called spike protein, is a multifunctional tool. It homes in on a cellular lock called ACE2—a blood pressure-regulating protein thought to be universal among vertebrates, the group that includes mammals, reptiles, birds, amphibians and fish. The virus spike protein has two receptors binding domains or RBDs facing downward and another facing upward, these allow the virus to bind with and invade human cells. The virus targeted human ACE-2 receptors bonded with an amino acid to facilitate the virus to get dissolved into human cells. After, the virus uses the spike protein to penetrate inside the cell and releases RNA to take over the whole cell. The virus than hijack the cells to replicate it as a factory of viruses.

So why are we not calling the virus by its name SARS-CoV-2?

The WHO says that "from a risk communications perspective, using the name SARS can have unintended consequences in terms of creating unnecessary fear for some populations, especially in Asia which was worst affected by the SARS outbreak in 2003".

It says it refers to the virus carefully as “the virus responsible for COVID-19” in communications.

One of the mysteries of the new coronavirus is that it is deadlier for men than women.

As of April 7, 2,232 men had died of COVID-19 in New York City — the epicenter of infections in the U.S. — compared to 1,309 women, according to the city's health department.

When it came to hospitalizations, there were more than 40,000 male patients, compared to about 34,000 female patients. The COVID-19 death rate per 100,000 people in New York City stood at 55 for men and less than 30 for women. A recent study out of China found the coronavirus fatality rate for men was 2.8%, compared to 1.7% for women. Another Chinese analysis found men accounted for 60% of COVID‐19 patients.

When Italy recently reported the country’s death toll, 72% of those who had died were men, according to the BBC. One study put the number even higher, with men making up 80% of people who had passed died in Italy.

Experts have suggested a number of factors that may help explain the disparity, including immune system differences between men and women, the protective effect of estrogen, lifestyle habits and the tendency for men to have more risk factors.

For example, men are more likely to smoke — with 40% of men smoking cigarettes worldwide compared to 9% of women, according to the World Health Organization — which puts them at higher risk of lung disease and a tougher battle when a respiratory virus strikes. Men also drink more alcohol and may put off going to a doctor when feeling unwell.


Written By Souradipta Gupta


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